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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KB2
All Species:
27.27
Human Site:
S428
Identified Species:
42.86
UniProt:
Q9UBS0
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBS0
NP_003943.2
482
53483
S428
P
V
S
P
L
K
F
S
P
F
E
G
F
R
P
Chimpanzee
Pan troglodytes
XP_001172909
482
53404
S428
P
I
S
P
L
K
F
S
P
F
E
G
F
R
P
Rhesus Macaque
Macaca mulatta
XP_001117937
512
56562
S455
P
I
S
P
L
K
F
S
P
F
E
G
F
R
P
Dog
Lupus familis
XP_851971
482
53401
S426
P
V
S
P
L
K
F
S
P
F
E
G
F
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1M4
485
53520
S428
P
I
S
P
L
K
F
S
P
F
E
G
F
R
P
Rat
Rattus norvegicus
P67999
525
59113
S452
P
V
S
P
V
K
F
S
P
G
D
F
W
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509850
482
54026
S409
P
V
S
P
V
K
F
S
P
G
D
F
W
G
R
Chicken
Gallus gallus
P18652
752
84421
E439
S
D
G
Y
V
V
K
E
A
I
G
V
G
S
Y
Frog
Xenopus laevis
P10665
733
82620
T421
D
V
Y
T
V
R
E
T
I
G
V
G
S
Y
S
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
D425
D
V
Y
E
L
K
E
D
I
G
V
G
S
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
E1059
P
V
S
V
A
T
Y
E
D
S
K
A
S
L
R
Honey Bee
Apis mellifera
XP_395876
456
51514
Q403
I
L
E
D
M
Y
S
Q
P
R
V
I
N
A
R
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
G463
I
L
E
K
I
G
N
G
A
H
S
V
V
H
K
Sea Urchin
Strong. purpuratus
XP_781234
487
53968
K433
R
S
A
I
S
P
A
K
T
P
Q
T
Q
F
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
S417
P
S
F
K
P
A
V
S
G
R
Q
C
I
A
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
91.8
95
N.A.
92.9
65.7
N.A.
70.9
30
30.5
30.2
N.A.
21.1
56.8
29.9
60.9
Protein Similarity:
100
99.7
92.5
96.6
N.A.
95
76
N.A.
80.9
42.8
42.5
43.2
N.A.
28.3
70.7
43.1
74.5
P-Site Identity:
100
93.3
93.3
100
N.A.
93.3
53.3
N.A.
53.3
0
13.3
26.6
N.A.
20
6.6
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
73.3
N.A.
73.3
6.6
33.3
26.6
N.A.
33.3
20
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
7
7
0
14
0
0
7
0
14
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
14
7
0
7
0
0
0
7
7
0
14
0
0
0
0
% D
% Glu:
0
0
14
7
0
0
14
14
0
0
34
0
0
0
0
% E
% Phe:
0
0
7
0
0
0
47
0
0
34
0
14
34
7
0
% F
% Gly:
0
0
7
0
0
7
0
7
7
27
7
47
7
14
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
7
0
% H
% Ile:
14
20
0
7
7
0
0
0
14
7
0
7
7
0
0
% I
% Lys:
0
0
0
14
0
54
7
7
0
0
7
0
0
0
7
% K
% Leu:
0
14
0
0
40
0
0
0
0
0
0
0
0
7
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
7
% N
% Pro:
60
0
0
47
7
7
0
0
54
7
0
0
0
0
34
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
14
0
7
0
0
% Q
% Arg:
7
0
0
0
0
7
0
0
0
14
0
0
0
34
27
% R
% Ser:
7
14
54
0
7
0
7
54
0
7
7
0
20
7
14
% S
% Thr:
0
0
0
7
0
7
0
7
7
0
0
7
0
0
0
% T
% Val:
0
47
0
7
27
7
7
0
0
0
20
14
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% W
% Tyr:
0
0
14
7
0
7
7
0
0
0
0
0
0
14
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _